美国宾大医学院和费城儿童医院博士后职位

  美国宾大医学院和费城儿童医院博士后职位,以下是厚谱教育为您收集整理的美国宾大医学院和费城儿童医院博士后详细招聘信息。

  Postdoc fellow – Ribosome biogenesis and ubiquitin signaling in stem cells and leukemia

  A postdoctoral fellow position is available at the University of Pennsylvania School of Medicine and the Children’s Hospital of Philadelphia, to investigate ribosome biogenesis and ubiquitin signaling in hematopoietic stem cells as well as leukemia. Hematopoietic stem cells give rise to all circulating blood cells throughout life. Maintenance of stem cell self-renewal, proliferation and differentiation is regulated by complex signaling pathways. Aberrant regulation leads to bone marrow failure or leukemia. Dr. Tong’s laboratory studies various signaling pathways in hematopoietic stem cells, bone marrow failure, and leukemia. Her laboratory recently identified a novel E3 ubiquitin ligase that plays a critical role in ribosome assembly and thereby controls hematopoietic stem cell regeneration. This postdoctoral fellow position will focus on studying the mechanisms by which ubiquitin-dependent signaling and ribosome biogenesis in regulating stem cells and investigating how failures in these processes impact hematopoietic stem cell function that leads to bone marrow failure and/or leukemia. Our recent publications include: Cell Stem Cell, March 11, 2021; Nature communications 9(1): 3915, Sep 2018; Genes & development 31(10): 1007-1023, May 2017; Blood 133(14): 1560-1571, Apr 2019. You can find more of our recent publication and laboratory information in below website.

  费城儿童医院(CHOP)是美国先专门为儿童提供医疗服务的医院。自1855年医院成立以来,CHOP诞生了多个儿科领域的记录。许多提高儿科医疗水平和拯救无数儿童生命的医学发现和创新来自CHOP。来自世界各地,面临复杂医学难题的患儿和家长来到费城就医,CHOP的医疗服务和创新使其多次入选“美国新闻与世界报道”评选的美国佳儿童医院,在历年公布的佳儿童医院排行榜中入选次数多,平均位次高,业内业外口碑俱佳。

  医院历史:

  1855年,Francis West Lewis博士建立CHOP。他在伦敦大奥蒙德街医院探望过患病儿童后,决定在美国建立先专门为儿童疾病和伤痛提供医护服务的医院。医院成立之初时,只有12张床位和1个药房。医生负责为67名住院患者和306名门诊患者提供服务。今天,CHOP已经拥有527张床位和每年100多万门诊和住院接待量。